{"id":61689,"date":"2021-04-21T12:57:12","date_gmt":"2021-04-21T10:57:12","guid":{"rendered":"https:\/\/wpcalc.com\/?p=61689"},"modified":"2026-10-01T13:26:20","modified_gmt":"2026-10-01T10:26:20","slug":"dextrose-intravenous-target-concentration","status":"publish","type":"post","link":"https:\/\/wpcalc.com\/en\/medical\/dextrose-intravenous-target-concentration\/","title":{"rendered":"Dextrose Intravenous Target Concentration Calculator"},"content":{"rendered":"<section class=\"not-prose calculator-box\" aria-labelledby=\"calculator-title\"><div class=\"flex items-baseline sm:items-center justify-between gap-2 sm:gap-3\"><div class=\"flex flex-col sm:flex-row sm:items-center gap-2\"><span class=\"icon icon-calculator text-primary-700! text-base! dark:text-primary-300!\" aria-hidden=\"true\"><\/span><h2 id=\"calculator-title\" class=\"text-lg font-display font-bold\">Dextrose Intravenous Target Concentration<\/h2><\/div><div class=\"calcdash-favorite group\">\n  <button type=\"button\" class=\"favorite\" id=\"favorite\" data-favorite-id=\"61689\" data-favorite-title=\"Dextrose Intravenous Target Concentration\" data-favorite-url=\"https:\/\/wpcalc.com\/en\/medical\/dextrose-intravenous-target-concentration\/\" data-favorite-excerpt=\"Calculate the final dextrose concentration when mixing two IV solutions (e.g. D50 with D5 or free water). Enter the volume and strength of each solution to get the resulting mixture&#039;s volume and dextrose percentage.\" aria-label=\"Add to Favorites\" data-favorite-icon=\"icon icon-pharmacology\">\n    <span class=\"icon icon-shape-star-empty\" aria-hidden=\"true\"><\/span>\n  <\/button>\n  <div class=\"calcdash-favorite__tip\" aria-hidden=\"true\">\n   <span class=\"favorite-tooltip\" id=\"favorite-tooltip\"><\/span>\n  <\/div>\n  <span class=\"sr-only\" role=\"status\" id=\"favorite-status\"><\/span>\n<\/div><\/div><form action=\"https:\/\/wpcalc.com\/en\/medical\/dextrose-intravenous-target-concentration\/\" method=\"POST\" class=\"calculator\" id=\"calculator-61689\" data-post=\"61689\"><fieldset class=\"fieldset-input is-1\"><legend class=\"sr-only\">Input Fields<\/legend><div class=\"field\" id=\"input-1\"><label for=\"field-1\">Base solution<\/label><div class=\"field-group\"><input type=\"number\" name=\"base_solution\" id=\"field-1\" aria-describedby=\"calc-unit-1\" placeholder=\"Volume\" step=\"any\" value=\"50\"\/><div class=\"unit\" id=\"calc-unit-1\">mL<\/div><div class=\"grid grid-cols-1\"><select id=\"field-2\" name=\"base_solution_water\" aria-label=\"Base solution water\"><option value=\"0\">Free water<\/option><option value=\"70\">D70<\/option><option value=\"50\">D50<\/option><option value=\"25\">D25<\/option><option value=\"10\" selected>D10<\/option><option value=\"5\">D5<\/option><\/select><svg class=\"pointer-events-none col-start-1 row-start-1 mr-2 size-5 self-center justify-self-end text-gray-500 sm:size-4\" viewBox=\"0 0 16 16\" fill=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\">\n              <path fill-rule=\"evenodd\" d=\"M4.22 6.22a.75.75 0 0 1 1.06 0L8 8.94l2.72-2.72a.75.75 0 1 1 1.06 1.06l-3.25 3.25a.75.75 0 0 1-1.06 0L4.22 7.28a.75.75 0 0 1 0-1.06Z\" clip-rule=\"evenodd\" \/>\n            <\/svg><\/div><\/div><\/div><div class=\"field\" id=\"input-2\"><label for=\"field-3\">Mix with<\/label><div class=\"field-group\"><input type=\"number\" name=\"mix_with\" id=\"field-3\" aria-describedby=\"calc-unit-3\" placeholder=\"Volume\" step=\"any\" value=\"50\"\/><div class=\"unit\" id=\"calc-unit-3\">mL<\/div><div class=\"grid grid-cols-1\"><select id=\"field-4\" name=\"mix_with_water\" aria-label=\"Mix with water\"><option value=\"0\">Free water<\/option><option value=\"70\">D70<\/option><option value=\"50\">D50<\/option><option value=\"25\">D25<\/option><option value=\"10\">D10<\/option><option value=\"5\" selected>D5<\/option><\/select><svg class=\"pointer-events-none col-start-1 row-start-1 mr-2 size-5 self-center justify-self-end text-gray-500 sm:size-4\" viewBox=\"0 0 16 16\" fill=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\">\n              <path fill-rule=\"evenodd\" d=\"M4.22 6.22a.75.75 0 0 1 1.06 0L8 8.94l2.72-2.72a.75.75 0 1 1 1.06 1.06l-3.25 3.25a.75.75 0 0 1-1.06 0L4.22 7.28a.75.75 0 0 1 0-1.06Z\" clip-rule=\"evenodd\" \/>\n            <\/svg><\/div><\/div><\/div><\/fieldset><div class=\"buttons\"><button type=\"submit\" data-text=\"Re-Calculate\" id=\"calculate-button\" data-post=\"61689\">Calculate<\/button><button type=\"reset\">Reset<\/button><\/div><div class=\"field is-checkbox hidden!\" id=\"field-auto-calc\"><input type=\"checkbox\" id=\"auto-calc\"><label for=\"auto-calc\">Calculate automatically<\/label><small>If enabled, the result will update automatically when you change any value.<\/small><\/div><div class=\"fieldset-result is-hidden\" aria-labelledby=\"result-title\" aria-live=\"polite\" role=\"region\"> <h3 class=\"result-title bg-gradient-to-r from-primary-50 to-gray-50 dark:from-primary-900 dark:to-gray-800\" id=\"result-title\"><span class=\"icon icon-s-pulse\" aria-hidden=\"true\"><\/span> Your Results<\/h3><div class=\"result-box\"><div class=\"field-result\" id=\"output-1\"><span class=\"field-title\"><span>Target solution dextrose:<\/span><\/span><span class=\"field-value\" id=\"result-1\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Copy Result\" aria-label=\"Copy Result\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><div class=\"field-result\" id=\"output-2\"><span class=\"field-title\"><span>Concentration:<\/span><\/span><span class=\"field-value\" id=\"result-2\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Copy Result\" aria-label=\"Copy Result\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><\/div><div class=\"result-actions\"><button type=\"button\" class=\"copy-link\"><svg viewBox=\"0 0 20 20\" fill=\"currentColor\" aria-hidden=\"true\"><path d=\"M12.232 4.232a2.5 2.5 0 0 1 3.536 3.536l-1.225 1.224a.75.75 0 0 0 1.061 1.06l1.224-1.224a4 4 0 0 0-5.656-5.656l-3 3a4 4 0 0 0 .225 5.865.75.75 0 0 0 .977-1.138 2.5 2.5 0 0 1-.142-3.667l3-3Z\"\/><path d=\"M11.603 7.963a.75.75 0 0 0-.977 1.138 2.5 2.5 0 0 1 .142 3.667l-3 3a2.5 2.5 0 0 1-3.536-3.536l1.225-1.224a.75.75 0 0 0-1.061-1.06l-1.224 1.224a4 4 0 1 0 5.656 5.656l3-3a4 4 0 0 0-.225-5.865Z\"\/><\/svg><span class=\"copy-link__text\">Copy link to this calculation<\/span><\/button><span class=\"sr-only\" role=\"status\" id=\"copy-link-status\"><\/span><\/div><\/div><a href=\"#respond\" class=\"hidden transition-opacity duration-300 opacity-0 w-50 text-sm justify-center items-center gap-2 px-4 py-2 rounded bg-gray-200 text-gray-700 hover:bg-gray-300\" id=\"leave-comment\"><span class=\"icon icon-comments\" aria-hidden=\"true\"><\/span>Leave a Comment<\/a><\/form><\/section><section id=\"calc-reactions\" class=\"not-prose hidden my-12 bg-gradient-to-r from-primary-50 to-gray-50 border border-indigo-100 rounded-xl px-6 py-4 shadow-sm\" data-post=\"61689\" aria-live=\"polite\" aria-labelledby=\"calc-reactions-title\"><p id=\"calc-reactions-title\" class=\"text-sm text-gray-500 text-center mb-2\">How did this result make you feel?<\/p><div role=\"group\" aria-labelledby=\"calc-reactions-title\" class=\"grid grid-cols-3 sm:flex sm:flex-row sm:justify-around gap-4 sm:items-center sm:flex-wrap\"><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"like\"><span class=\"reaction-count\" data-reaction-count=\"like\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude00 <\/span><span class=\"reaction-description font-medium\">Like <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"helpful\"><span class=\"reaction-count\" data-reaction-count=\"helpful\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\udca1 <\/span><span class=\"reaction-description font-medium\">Helpful <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"confused\"><span class=\"reaction-count\" data-reaction-count=\"confused\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude15 <\/span><span class=\"reaction-description font-medium\">Confused <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"disappointed\"><span class=\"reaction-count\" data-reaction-count=\"disappointed\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude1e <\/span><span class=\"reaction-description font-medium\">Disappointed <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"inaccurate\"><span class=\"reaction-count\" data-reaction-count=\"inaccurate\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\u274c <\/span><span class=\"reaction-description font-medium\">Inaccurate <\/span><\/button><\/div><div id=\"reaction-message\" class=\"hidden mt-8 rounded-md border border-primary-100 bg-white\/50 backdrop-blur-sm px-4 py-2 text-sm text-center shadow-sm\"><\/div><\/section><div class=\"calcdash-ad not-prose calcdash-ad--calc_result calcdash-ad--in-article\"><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-client=\"ca-pub-1721569815777345\" data-ad-slot=\"6317458308\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/div>\n<style id=\"wpcoderpro-inline-1\">.formula-box {\r\n\tborder-bottom: none !important;\r\n}<\/style><section class=\"formula-box\" aria-labelledby=\"formula-title\">\r\n\t<div id=\"formula-title\" class=\"not-prose font-display mb-4\"><span class=\"icon icon-formula\" aria-hidden=\"true\"><\/span><h2>Dextrose Intravenous Target Concentration Formula<\/h2><\/div>\r\n\t<figure class=\"not-prose formula\">\r\n\t\t<figcaption class=\"formula-title\">Formula<\/figcaption>\r\n\t\t<div class=\"text-base text-gray-800\" id=\"formula\">\n\\[ C_{\\text{target}} = \\frac{V_1 \\times C_1 + V_2 \\times C_2}{V_1 + V_2} \\]\n<\/div>\r\n\t<\/figure>\r\n\t<\/p>\n<p><strong>Where:<\/strong><\/p>\n<ul>\n<li>\\(V_1\\) \u2014 volume of the base solution (mL)<\/li>\n<li>\\(C_1\\) \u2014 dextrose concentration of the base solution (%)<\/li>\n<li>\\(V_2\\) \u2014 volume of the solution mixed in (mL)<\/li>\n<li>\\(C_2\\) \u2014 dextrose concentration of the mixed-in solution (%)<\/li>\n<\/ul>\n<p>The numerator adds up the grams of dextrose contributed by each solution, and dividing by the total volume gives the concentration of the final mixture. Free water counts as 0% dextrose.<\/p>\n<p>\r\n<\/section>\n<style id=\"wpcoderpro-inline-459\">.calculation-box {\r\n\tborder-bottom: none !important;\r\n}<\/style><section id=\"calculation\" class=\"calculation-box\" aria-labelledby=\"calculation-title\">\r\n\t<div id=\"calculation-title\" class=\"not-prose font-display\"><span class=\"icon icon-unordered-list\" aria-hidden=\"true\"><\/span><h2>Dextrose Intravenous Target Concentration \u2013 Calculation Example<\/h2><\/div>\r\n\r\n<\/p>\n<p><strong>Example:<\/strong> 50 mL of D10 (10% dextrose) is mixed with 50 mL of D5 (5% dextrose).<\/p>\n<p>\\[ C_{\\text{target}} = \\frac{50 \\times 10 + 50 \\times 5}{50 + 50} = \\frac{500 + 250}{100} = 7.5 \\% \\]<\/p>\n<p><strong>Result:<\/strong> the target solution has a total volume of 100 mL and a dextrose concentration of 7.5% (7.5 g of dextrose per 100 mL).<\/p>\n<p>\n\r\n<\/section>\n<h2>How to Use the Calculator<\/h2>\n<ol>\n<li>In the <strong>Base solution<\/strong> field, enter the volume (in mL) of the solution you are starting with.<\/li>\n<li>From the dropdown next to it, choose the dextrose strength of the base solution: Free water (0%), D5, D10, D25, D50 or D70.<\/li>\n<li>In the <strong>Mix with<\/strong> field, enter the volume (in mL) of the second solution.<\/li>\n<li>Select its dextrose strength from the dropdown in the same way.<\/li>\n<li>Read the results: the calculator shows the total volume of the target solution and its final dextrose concentration as a percentage.<\/li>\n<\/ol>\n<h2>What Is a Dextrose Target Concentration?<\/h2>\n<p>Dextrose (glucose) solutions for intravenous use are labeled by the grams of dextrose per 100 mL of solution: D5 contains 5 g\/100 mL, D10 contains 10 g\/100 mL, and so on. Standard commercial concentrations do not always match what a patient needs. Neonatal units, for example, frequently require intermediate concentrations, and fluid-restricted patients may need higher dextrose delivered in less volume.<\/p>\n<p>When two solutions are mixed, the resulting concentration always falls between the two starting concentrations \u2014 it is a weighted average in which each solution's contribution depends on its volume. Mixing D50 with free water dilutes it; mixing D5 with D25 concentrates it. This weighted-average principle is exactly what the formula above expresses.<\/p>\n<p>A common source of confusion is the difference between concentration and total dextrose. A 100 mL bag of D10 and a 1000 mL bag of D10 have the same concentration (10%) but deliver very different amounts of glucose (10 g vs 100 g). When preparing custom mixtures, both the final concentration and the total grams of dextrose delivered matter, especially for infants and patients on strict glucose and fluid balance targets. If you also track infusion rates, our <a href=\"https:\/\/wpcalc.com\/en\/medical\/dosage-infusion\/\">Dosage Infusion calculator<\/a> can help convert the mixture into a dosing rate.<\/p>\n<h2>Assumptions, Limitations and Practical Tips<\/h2>\n<ul>\n<li><strong>Volumes are additive.<\/strong> The calculator assumes the final volume equals the sum of the two input volumes. In practice, small volume changes can occur when mixing, so verify the final product against institutional protocols.<\/li>\n<li><strong>Percentages are weight\/volume (g per 100 mL).<\/strong> A 10% solution contains 10 g of dextrose per 100 mL, which is the standard convention for IV dextrose products.<\/li>\n<li><strong>Free water is treated as 0% dextrose.<\/strong> Selecting \"Free water\" in either dropdown simply adds volume without adding dextrose, diluting the mixture.<\/li>\n<li><strong>Sterility and compatibility.<\/strong> This calculator performs arithmetic only. Actual preparation of IV admixtures must follow aseptic technique, pharmacy procedures and compatibility guidelines \u2014 never mix solutions without confirming they are intended for combination.<\/li>\n<li><strong>Double-check high-strength mixtures.<\/strong> Working with D50 and D70 carries a high risk of dosing errors. Have the calculation independently verified before administration, per medication-safety practice.<\/li>\n<li>For related calculations, see the <a href=\"https:\/\/wpcalc.com\/en\/medical\/liquid-dose-medicine\/\">Liquid Dose calculator<\/a> for liquid medication dosing, or the <a href=\"https:\/\/wpcalc.com\/en\/medical\/hyperglycemia-sodium-correction\/\">Corrected Sodium (Hyperglycemia)<\/a> calculator when managing sodium values in hyperglycemic patients.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Calculate the final dextrose concentration when mixing two IV solutions (e.g. D50 with D5 or free water). Enter the volume and strength of each solution to get the resulting mixture's volume and dextrose percentage.<\/p>\n","protected":false},"author":70,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8],"tags":[32],"class_list":["post-61689","post","type-post","status-publish","format-standard","hentry","category-medical","tag-pharmacology"],"acf":[],"_links":{"self":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts\/61689","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/users\/70"}],"replies":[{"embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/comments?post=61689"}],"version-history":[{"count":3,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts\/61689\/revisions"}],"predecessor-version":[{"id":66317,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts\/61689\/revisions\/66317"}],"wp:attachment":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/media?parent=61689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/categories?post=61689"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/tags?post=61689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}