{"id":61708,"date":"2021-04-21T18:32:45","date_gmt":"2021-04-21T16:32:45","guid":{"rendered":"https:\/\/wpcalc.com\/?p=61708"},"modified":"2026-10-23T16:30:51","modified_gmt":"2026-10-23T13:30:51","slug":"hyperglycemia-sodium-correction","status":"publish","type":"post","link":"https:\/\/wpcalc.com\/en\/medical\/hyperglycemia-sodium-correction\/","title":{"rendered":"Corrected Sodium Calculator \u2013 Sodium Correction for Glucose"},"content":{"rendered":"<section class=\"not-prose calculator-box\" aria-labelledby=\"calculator-title\"><div class=\"flex items-baseline sm:items-center justify-between gap-2 sm:gap-3\"><div class=\"flex flex-col sm:flex-row sm:items-center gap-2\"><span class=\"icon icon-calculator text-primary-700! text-base! dark:text-primary-300!\" aria-hidden=\"true\"><\/span><h2 id=\"calculator-title\" class=\"text-lg font-display font-bold\">Hyperglycemia Sodium Correction<\/h2><\/div><div class=\"calcdash-favorite group\">\n  <button type=\"button\" class=\"favorite\" id=\"favorite\" data-favorite-id=\"61708\" data-favorite-title=\"Corrected Sodium (Hyperglycemia)\" data-favorite-url=\"https:\/\/wpcalc.com\/en\/medical\/hyperglycemia-sodium-correction\/\" data-favorite-excerpt=\"Estimates corrected serum sodium in hyperglycemia using the Katz (1.6 mEq\/L per 100 mg\/dL) and Hillier (2.4 mEq\/L) correction factors. Enter measured sodium and serum glucose to see both results.\" aria-label=\"Add to Favorites\" data-favorite-icon=\"icon icon-pharmacology\">\n    <span class=\"icon icon-shape-star-empty\" aria-hidden=\"true\"><\/span>\n  <\/button>\n  <div class=\"calcdash-favorite__tip\" aria-hidden=\"true\">\n   <span class=\"favorite-tooltip\" id=\"favorite-tooltip\"><\/span>\n  <\/div>\n  <span class=\"sr-only\" role=\"status\" id=\"favorite-status\"><\/span>\n<\/div><\/div><form action=\"https:\/\/wpcalc.com\/en\/medical\/hyperglycemia-sodium-correction\/\" method=\"POST\" class=\"calculator\" id=\"calculator-61708\" data-post=\"61708\"><fieldset class=\"fieldset-input is-1\"><legend class=\"sr-only\">Input Fields<\/legend><div class=\"field has-term\" id=\"input-1\"><label for=\"field-1\">Measured sodium<\/label><div class=\"term\">Na<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><input type=\"text\" name=\"measured_sodium\" id=\"field-1\" aria-describedby=\"calc-unit-1\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" placeholder=\"Sodium (mEq\/L)\" min=\"100\" max=\"160\" value=\"135\"\/><div class=\"unit\" id=\"calc-unit-1\">mEq\/L<\/div><\/div><div class=\"field has-term\" id=\"input-2\"><label for=\"field-2\">Serum glucose<\/label><div class=\"term\">Glu<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><input type=\"text\" name=\"serum_glucose\" id=\"field-2\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" placeholder=\"Glucose\" min=\"70\" max=\"105\" value=\"90\"\/><\/div><div class=\"field\" id=\"input-3\"><label for=\"field-3\">Glucose unit<\/label><div class=\"grid grid-cols-1\"><select id=\"field-3\" name=\"glucose_unit\"><option value=\"1\">mg\/dL<\/option><option value=\"2\">mmol\/L<\/option><\/select><svg class=\"pointer-events-none col-start-1 row-start-1 mr-2 size-5 self-center justify-self-end text-gray-500 sm:size-4\" viewBox=\"0 0 16 16\" fill=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\">\n              <path fill-rule=\"evenodd\" d=\"M4.22 6.22a.75.75 0 0 1 1.06 0L8 8.94l2.72-2.72a.75.75 0 1 1 1.06 1.06l-3.25 3.25a.75.75 0 0 1-1.06 0L4.22 7.28a.75.75 0 0 1 0-1.06Z\" clip-rule=\"evenodd\" \/>\n            <\/svg><\/div><\/div><\/fieldset><div class=\"buttons\"><button type=\"submit\" data-text=\"Re-Calculate\" id=\"calculate-button\" data-post=\"61708\">Calculate<\/button><button type=\"reset\">Reset<\/button><\/div><div class=\"field is-checkbox hidden!\" id=\"field-auto-calc\"><input type=\"checkbox\" id=\"auto-calc\"><label for=\"auto-calc\">Calculate automatically<\/label><small>If enabled, the result will update automatically when you change any value.<\/small><\/div><div class=\"fieldset-result is-hidden\" aria-labelledby=\"result-title\" aria-live=\"polite\" role=\"region\"> <h3 class=\"result-title bg-gradient-to-r from-primary-50 to-gray-50 dark:from-primary-900 dark:to-gray-800\" id=\"result-title\"><span class=\"icon icon-s-pulse\" aria-hidden=\"true\"><\/span> Your Results<\/h3><div class=\"result-box\"><div class=\"field-result\" id=\"output-1\"><span class=\"field-title\"><span>Corrected sodium (Katz, 1973):<\/span><\/span><span class=\"field-value\" id=\"result-1\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Copy Result\" aria-label=\"Copy Result\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><div class=\"field-result\" id=\"output-2\"><span class=\"field-title\"><span>Corrected sodium (Hillier, 1999):<\/span><\/span><span class=\"field-value\" id=\"result-2\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Copy Result\" aria-label=\"Copy Result\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><\/div><div class=\"result-actions\"><button type=\"button\" class=\"copy-link\"><svg viewBox=\"0 0 20 20\" fill=\"currentColor\" aria-hidden=\"true\"><path d=\"M12.232 4.232a2.5 2.5 0 0 1 3.536 3.536l-1.225 1.224a.75.75 0 0 0 1.061 1.06l1.224-1.224a4 4 0 0 0-5.656-5.656l-3 3a4 4 0 0 0 .225 5.865.75.75 0 0 0 .977-1.138 2.5 2.5 0 0 1-.142-3.667l3-3Z\"\/><path d=\"M11.603 7.963a.75.75 0 0 0-.977 1.138 2.5 2.5 0 0 1 .142 3.667l-3 3a2.5 2.5 0 0 1-3.536-3.536l1.225-1.224a.75.75 0 0 0-1.061-1.06l-1.224 1.224a4 4 0 1 0 5.656 5.656l3-3a4 4 0 0 0-.225-5.865Z\"\/><\/svg><span class=\"copy-link__text\">Copy link to this calculation<\/span><\/button><span class=\"sr-only\" role=\"status\" id=\"copy-link-status\"><\/span><\/div><\/div><a href=\"#respond\" class=\"hidden transition-opacity duration-300 opacity-0 w-50 text-sm justify-center items-center gap-2 px-4 py-2 rounded bg-gray-200 text-gray-700 hover:bg-gray-300\" id=\"leave-comment\"><span class=\"icon icon-comments\" aria-hidden=\"true\"><\/span>Leave a Comment<\/a><\/form><\/section><section id=\"calc-reactions\" class=\"not-prose hidden my-12 bg-gradient-to-r from-primary-50 to-gray-50 border border-indigo-100 rounded-xl px-6 py-4 shadow-sm\" data-post=\"61708\" aria-live=\"polite\" aria-labelledby=\"calc-reactions-title\"><p id=\"calc-reactions-title\" class=\"text-sm text-gray-500 text-center mb-2\">How did this result make you feel?<\/p><div role=\"group\" aria-labelledby=\"calc-reactions-title\" class=\"grid grid-cols-3 sm:flex sm:flex-row sm:justify-around gap-4 sm:items-center sm:flex-wrap\"><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"like\"><span class=\"reaction-count\" data-reaction-count=\"like\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude00 <\/span><span class=\"reaction-description font-medium\">Like <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"helpful\"><span class=\"reaction-count\" data-reaction-count=\"helpful\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\udca1 <\/span><span class=\"reaction-description font-medium\">Helpful <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"confused\"><span class=\"reaction-count\" data-reaction-count=\"confused\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude15 <\/span><span class=\"reaction-description font-medium\">Confused <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"disappointed\"><span class=\"reaction-count\" data-reaction-count=\"disappointed\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude1e <\/span><span class=\"reaction-description font-medium\">Disappointed <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"inaccurate\"><span class=\"reaction-count\" data-reaction-count=\"inaccurate\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\u274c <\/span><span class=\"reaction-description font-medium\">Inaccurate <\/span><\/button><\/div><div id=\"reaction-message\" class=\"hidden mt-8 rounded-md border border-primary-100 bg-white\/50 backdrop-blur-sm px-4 py-2 text-sm text-center shadow-sm\"><\/div><\/section><div class=\"calcdash-ad not-prose calcdash-ad--calc_result calcdash-ad--in-article\"><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-client=\"ca-pub-1721569815777345\" data-ad-slot=\"6317458308\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/div>\n<style id=\"wpcoderpro-inline-1\">.formula-box {\r\n\tborder-bottom: none !important;\r\n}<\/style><section class=\"formula-box\" aria-labelledby=\"formula-title\">\r\n\t<div id=\"formula-title\" class=\"not-prose font-display mb-4\"><span class=\"icon icon-formula\" aria-hidden=\"true\"><\/span><h2>Corrected Sodium Formula (Katz and Hillier)<\/h2><\/div>\r\n\t<figure class=\"not-prose formula\">\r\n\t\t<figcaption class=\"formula-title\">Formula<\/figcaption>\r\n\t\t<div class=\"text-base text-gray-800\" id=\"formula\">\n\\[ \\text{Na}_{\\text{corrected}} = \\text{Na}_{\\text{measured}} + 1.6 \\times \\frac{\\text{Glucose} - 100}{100} \\]\n\\[ \\text{Na}_{\\text{corrected}} = \\text{Na}_{\\text{measured}} + 2.4 \\times \\frac{\\text{Glucose} - 100}{100} \\]\n<\/div>\r\n\t<\/figure>\r\n\t<\/p>\n<p><strong>Where:<\/strong><\/p>\n<ul>\n<li>\\(\\text{Na}_{\\text{measured}}\\) \u2014 serum sodium from the laboratory report (mEq\/L)<\/li>\n<li>\\(\\text{Glucose}\\) \u2014 serum glucose in mg\/dL (if measured in mmol\/L, multiply by 18.0182 first)<\/li>\n<li>\\(1.6\\) \u2014 correction factor of Katz (1973), in mEq\/L of sodium per 100 mg\/dL of glucose above 100<\/li>\n<li>\\(2.4\\) \u2014 correction factor of Hillier (1999), in mEq\/L per 100 mg\/dL above 100<\/li>\n<\/ul>\n<p>The first equation is the classic Katz correction; the second is the Hillier correction, which accounts for the stronger sodium\u2013glucose relationship observed at very high glucose concentrations. Both express the same idea: for every 100 mg\/dL that glucose rises above 100 mg\/dL, serum sodium falls by a predictable amount because water is drawn out of cells into the extracellular space.<\/p>\n<p>\r\n<\/section>\n<style id=\"wpcoderpro-inline-459\">.calculation-box {\r\n\tborder-bottom: none !important;\r\n}<\/style><section id=\"calculation\" class=\"calculation-box\" aria-labelledby=\"calculation-title\">\r\n\t<div id=\"calculation-title\" class=\"not-prose font-display\"><span class=\"icon icon-unordered-list\" aria-hidden=\"true\"><\/span><h2>Corrected Sodium \u2013 Calculation Example<\/h2><\/div>\r\n\r\n<\/p>\n<p><strong>Example:<\/strong> a patient with diabetic ketoacidosis has a measured serum sodium of 130 mEq\/L and a serum glucose of 600 mg\/dL.<\/p>\n<p>\\[ \\text{Katz:} \\quad 130 + 1.6 \\times \\frac{600 - 100}{100} = 130 + 1.6 \\times 5 = 138 \\text{ mEq\/L} \\]<\/p>\n<p>\\[ \\text{Hillier:} \\quad 130 + 2.4 \\times \\frac{600 - 100}{100} = 130 + 2.4 \\times 5 = 142 \\text{ mEq\/L} \\]<\/p>\n<p><strong>Result:<\/strong> the corrected sodium is 138 mEq\/L by the Katz method and 142 mEq\/L by the Hillier method. Despite a measured sodium of 130 mEq\/L suggesting hyponatremia, the corrected values show the true sodium status is normal or even elevated, which changes both diagnosis and fluid management.<\/p>\n<p>\n\r\n<\/section>\n<h2>How to use the calculator<\/h2>\n<ol>\n<li>Enter the <strong>Measured sodium<\/strong> value from the patient's chemistry panel in mEq\/L.<\/li>\n<li>Enter the <strong>Serum glucose<\/strong> value from the same or a recent blood draw.<\/li>\n<li>Select the correct <strong>Glucose unit<\/strong> \u2014 mg\/dL or mmol\/L. The calculator converts mmol\/L to mg\/dL automatically (multiply by 18.0182).<\/li>\n<li>Read both results: <strong>Corrected sodium (Katz, 1973)<\/strong> and <strong>Corrected sodium (Hillier, 1999)<\/strong>, each in mEq\/L.<\/li>\n<li>If the two values differ substantially, note that the gap widens at higher glucose levels and interpret both together with the clinical picture.<\/li>\n<\/ol>\n<h2>What is corrected sodium and why does it matter?<\/h2>\n<p>Corrected sodium estimates what the serum sodium <em>would<\/em> be if the elevated glucose were brought down to a normal level of about 100 mg\/dL. High blood glucose creates an osmotic gradient that pulls water from the intracellular space into the blood vessels, diluting the sodium concentration in serum. This is called <strong>translocational hyponatremia<\/strong>: the measured sodium is low, but no sodium has actually been lost from the body.<\/p>\n<p>The consequence is practical. In a hyperglycemic patient with a measured sodium of 130 mEq\/L, the corrected value may be entirely normal. Treating such a patient with aggressive hypertonic saline would be a mistake; the correct treatment is insulin and fluids to lower glucose, after which the sodium will rise on its own \u2014 typically by about 1.6\u20132.4 mEq\/L for every 100 mg\/dL that glucose falls. Corrected sodium therefore prevents both over-treatment of<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Estimates corrected serum sodium in hyperglycemia using the Katz (1.6 mEq\/L per 100 mg\/dL) and Hillier (2.4 mEq\/L) correction factors. Enter measured sodium and serum glucose to see both results.<\/p>\n","protected":false},"author":70,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8],"tags":[32],"class_list":["post-61708","post","type-post","status-publish","format-standard","hentry","category-medical","tag-pharmacology"],"acf":[],"_links":{"self":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts\/61708","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/users\/70"}],"replies":[{"embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/comments?post=61708"}],"version-history":[{"count":4,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts\/61708\/revisions"}],"predecessor-version":[{"id":67485,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/posts\/61708\/revisions\/67485"}],"wp:attachment":[{"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/media?parent=61708"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/categories?post=61708"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wpcalc.com\/en\/wp-json\/wp\/v2\/tags?post=61708"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}