{"id":4061,"date":"2026-10-15T02:15:31","date_gmt":"2026-10-15T01:15:31","guid":{"rendered":"https:\/\/wpcalc.com\/tr\/tisbi\/serum-ozmolalite-hesaplama\/"},"modified":"2026-10-15T02:15:31","modified_gmt":"2026-10-15T01:15:31","slug":"serum-ozmolalite-hesaplama","status":"publish","type":"post","link":"https:\/\/wpcalc.com\/tr\/tisbi\/serum-ozmolalite-hesaplama\/","title":{"rendered":"Serum Ozmolalite Hesaplama"},"content":{"rendered":"<section class=\"not-prose calculator-box\" aria-labelledby=\"calculator-title\"><div class=\"flex items-baseline sm:items-center justify-between gap-2 sm:gap-3\"><div class=\"flex flex-col sm:flex-row sm:items-center gap-2\"><span class=\"icon icon-calculator text-primary-700! text-base! dark:text-primary-300!\" aria-hidden=\"true\"><\/span><h2 id=\"calculator-title\" class=\"text-lg font-display font-bold\">Sodyum, Glukoz ve BUN De\u011ferlerinden Serum Ozmolalitesini Hesaplay\u0131n<\/h2><\/div><div class=\"calcdash-favorite group\">\n  <button type=\"button\" class=\"favorite\" id=\"favorite\" data-favorite-id=\"4061\" data-favorite-title=\"Serum Ozmolalite\" data-favorite-url=\"https:\/\/wpcalc.com\/tr\/tisbi\/serum-ozmolalite-hesaplama\/\" data-favorite-excerpt=\"Sodyum, glukoz, BUN ve istenirse etanol de\u011ferlerinden serum ozmolalitesini hesaplay\u0131n; \u00f6l\u00e7\u00fclm\u00fc\u015f bir de\u011fer varsa ozmolar a\u00e7\u0131kl\u0131\u011f\u0131 da bulun. mg\/dL veya mmol\/L cinsinden laboratuvar de\u011ferlerinizi girin, an\u0131nda yorumlay\u0131n.\" aria-label=\"Favorilere ekle\" data-favorite-icon=\"icon icon-flask\">\n    <span class=\"icon icon-shape-star-empty\" aria-hidden=\"true\"><\/span>\n  <\/button>\n  <div class=\"calcdash-favorite__tip\" aria-hidden=\"true\">\n   <span class=\"favorite-tooltip\" id=\"favorite-tooltip\"><\/span>\n  <\/div>\n  <span class=\"sr-only\" role=\"status\" id=\"favorite-status\"><\/span>\n<\/div><\/div><form action=\"https:\/\/wpcalc.com\/tr\/tisbi\/serum-ozmolalite-hesaplama\/\" method=\"POST\" class=\"calculator\" id=\"calculator-4061\" data-post=\"4061\"><fieldset class=\"fieldset-input is-2\"><legend class=\"sr-only\">Giri\u015f alanlar\u0131<\/legend><div class=\"field has-term\" id=\"input-1\"><label for=\"field-1\">Serum sodyumu<\/label><div class=\"term\">Na<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><input type=\"text\" name=\"serum_sodyumu\" id=\"field-1\" aria-describedby=\"calc-unit-1 calc-info-1\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" min=\"100\" max=\"180\" value=\"140\"\/><div class=\"unit\" id=\"calc-unit-1\">mEq\/L<\/div><small id=\"calc-info-1\">mmol\/L cinsinden ayn\u0131 say\u0131sal de\u011fer<\/small><\/div><div class=\"field has-term\" id=\"input-2\"><label for=\"field-2\">Serum glukozu<\/label><div class=\"term\">Glu<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><div class=\"field-group\"><input type=\"text\" name=\"serum_glukozu\" id=\"field-2\" aria-describedby=\"calc-info-2\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" min=\"1\" max=\"1500\" value=\"100\"\/><div class=\"grid grid-cols-1\"><select id=\"field-3\" name=\"birim\" aria-label=\"Birim\"><option value=\"mgdl\" selected>mg\/dL<\/option><option value=\"mmol\">mmol\/L<\/option><\/select><svg class=\"pointer-events-none col-start-1 row-start-1 mr-2 size-5 self-center justify-self-end text-gray-500 sm:size-4\" viewBox=\"0 0 16 16\" fill=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\">\n              <path fill-rule=\"evenodd\" d=\"M4.22 6.22a.75.75 0 0 1 1.06 0L8 8.94l2.72-2.72a.75.75 0 1 1 1.06 1.06l-3.25 3.25a.75.75 0 0 1-1.06 0L4.22 7.28a.75.75 0 0 1 0-1.06Z\" clip-rule=\"evenodd\" \/>\n            <\/svg><\/div><\/div><small id=\"calc-info-2\">Kan tahlili raporunuzdan al\u0131nan de\u011fer<\/small><\/div><div class=\"field has-term\" id=\"input-3\"><label for=\"field-4\">Kan \u00fcre azotu<\/label><div class=\"term\">BUN<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><div class=\"field-group\"><input type=\"text\" name=\"kan_re_azotu\" id=\"field-4\" aria-describedby=\"calc-info-4\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" min=\"0.5\" max=\"250\" value=\"15\"\/><div class=\"grid grid-cols-1\"><select id=\"field-5\" name=\"birim\" aria-label=\"Birim\"><option value=\"mgdl\" selected>mg\/dL<\/option><option value=\"mmol\">mmol\/L<\/option><\/select><svg class=\"pointer-events-none col-start-1 row-start-1 mr-2 size-5 self-center justify-self-end text-gray-500 sm:size-4\" viewBox=\"0 0 16 16\" fill=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\">\n              <path fill-rule=\"evenodd\" d=\"M4.22 6.22a.75.75 0 0 1 1.06 0L8 8.94l2.72-2.72a.75.75 0 1 1 1.06 1.06l-3.25 3.25a.75.75 0 0 1-1.06 0L4.22 7.28a.75.75 0 0 1 0-1.06Z\" clip-rule=\"evenodd\" \/>\n            <\/svg><\/div><\/div><small id=\"calc-info-4\">BUN; raporunuz mmol\/L kullan\u0131yorsa \u00fcre de\u011ferini girin<\/small><\/div><div class=\"field has-term\" id=\"input-4\"><label for=\"field-6\">Etil alkol (iste\u011fe ba\u011fl\u0131)<\/label><div class=\"term\">EtOH<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><div class=\"field-group\"><input type=\"text\" name=\"etil_alkol_istee_bal\" id=\"field-6\" aria-describedby=\"calc-info-6\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" min=\"0\" max=\"700\" value=\"0\"\/><div class=\"grid grid-cols-1\"><select id=\"field-7\" name=\"birim\" aria-label=\"Birim\"><option value=\"mgdl\" selected>mg\/dL<\/option><option value=\"mmol\">mmol\/L<\/option><\/select><svg class=\"pointer-events-none col-start-1 row-start-1 mr-2 size-5 self-center justify-self-end text-gray-500 sm:size-4\" viewBox=\"0 0 16 16\" fill=\"currentColor\" aria-hidden=\"true\" data-slot=\"icon\">\n              <path fill-rule=\"evenodd\" d=\"M4.22 6.22a.75.75 0 0 1 1.06 0L8 8.94l2.72-2.72a.75.75 0 1 1 1.06 1.06l-3.25 3.25a.75.75 0 0 1-1.06 0L4.22 7.28a.75.75 0 0 1 0-1.06Z\" clip-rule=\"evenodd\" \/>\n            <\/svg><\/div><\/div><small id=\"calc-info-6\">\u00d6l\u00e7\u00fclmediyse veya uygulanabilir de\u011filse 0 olarak b\u0131rak\u0131n<\/small><\/div><div class=\"field has-term\" id=\"input-5\"><label for=\"field-8\">\u00d6l\u00e7\u00fclen ozmolalite (iste\u011fe ba\u011fl\u0131)<\/label><div class=\"term\">Osm<\/div>  <div class=\"absolute bottom-0 left-16 top-8 w-2 h-0.5 bg-blue-500\"><\/div><input type=\"text\" name=\"llen_ozmolalite_istee_bal\" id=\"field-8\" aria-describedby=\"calc-unit-8 calc-info-8\" data-number inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" min=\"200\" max=\"400\"\/><div class=\"unit\" id=\"calc-unit-8\">mOsm\/kg<\/div><small id=\"calc-info-8\">Girilirse ozmolar gap hesaplan\u0131r<\/small><\/div><\/fieldset><div class=\"buttons\"><button type=\"submit\" data-text=\"Yeniden hesapla\" id=\"calculate-button\" data-post=\"4061\">Hesapla<\/button><button type=\"reset\">S\u0131f\u0131rla<\/button><\/div><div class=\"field is-checkbox hidden!\" id=\"field-auto-calc\"><input type=\"checkbox\" id=\"auto-calc\"><label for=\"auto-calc\">Otomatik hesapla<\/label><small>Etkinle\u015ftirilirse, herhangi bir de\u011feri de\u011fi\u015ftirdi\u011finizde sonu\u00e7 otomatik olarak g\u00fcncellenir.<\/small><\/div><div class=\"fieldset-result is-hidden\" aria-labelledby=\"result-title\" aria-live=\"polite\" role=\"region\"> <h3 class=\"result-title bg-gradient-to-r from-primary-50 to-gray-50 dark:from-primary-900 dark:to-gray-800\" id=\"result-title\"><span class=\"icon icon-s-pulse\" aria-hidden=\"true\"><\/span> Serum Ozmolalitesi Sonucunuz<\/h3><div class=\"result-box\"><div class=\"field-result\" id=\"output-1\"><span class=\"field-title\"><span>Hesaplanan serum ozmolalitesi<\/span><span class=\"result-term\">Osm<\/span><\/span><span class=\"field-value\" id=\"result-1\" data-unit=\"mOsm\/kg\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Sonucu kopyala\" aria-label=\"Sonucu kopyala\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><div class=\"field-result\" id=\"output-2\"><span class=\"field-title\"><span>Ozmolar gap<\/span><span class=\"result-term\">OG<\/span><\/span><span class=\"field-value\" id=\"result-2\" data-unit=\"mOsm\/kg\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Sonucu kopyala\" aria-label=\"Sonucu kopyala\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><div class=\"field-result is-column\" id=\"output-3\"><span class=\"field-title\"><span>Bu ne anlama geliyor<\/span><\/span><span class=\"field-value\" id=\"result-3\"><\/span><button type=\"button\" class=\"copy-result\" data-tooltip=\"Sonucu kopyala\" aria-label=\"Sonucu kopyala\"><span class=\"copy-icon icon icon-document-copy\" aria-hidden=\"true\"><\/span><\/button><\/div><\/div><div class=\"result-actions\"><button type=\"button\" class=\"copy-link\"><svg viewBox=\"0 0 20 20\" fill=\"currentColor\" aria-hidden=\"true\"><path d=\"M12.232 4.232a2.5 2.5 0 0 1 3.536 3.536l-1.225 1.224a.75.75 0 0 0 1.061 1.06l1.224-1.224a4 4 0 0 0-5.656-5.656l-3 3a4 4 0 0 0 .225 5.865.75.75 0 0 0 .977-1.138 2.5 2.5 0 0 1-.142-3.667l3-3Z\"\/><path d=\"M11.603 7.963a.75.75 0 0 0-.977 1.138 2.5 2.5 0 0 1 .142 3.667l-3 3a2.5 2.5 0 0 1-3.536-3.536l1.225-1.224a.75.75 0 0 0-1.061-1.06l-1.224 1.224a4 4 0 1 0 5.656 5.656l3-3a4 4 0 0 0-.225-5.865Z\"\/><\/svg><span class=\"copy-link__text\">Bu hesaplaman\u0131n ba\u011flant\u0131s\u0131n\u0131 kopyala<\/span><\/button><span class=\"sr-only\" role=\"status\" id=\"copy-link-status\"><\/span><\/div><\/div><a href=\"#respond\" class=\"hidden transition-opacity duration-300 opacity-0 w-50 text-sm justify-center items-center gap-2 px-4 py-2 rounded bg-gray-200 text-gray-700 hover:bg-gray-300\" id=\"leave-comment\"><span class=\"icon icon-comments\" aria-hidden=\"true\"><\/span>Yorum b\u0131rak<\/a><\/form><\/section><section id=\"calc-reactions\" class=\"not-prose hidden my-12 bg-gradient-to-r from-primary-50 to-gray-50 border border-indigo-100 rounded-xl px-6 py-4 shadow-sm\" data-post=\"4061\" aria-live=\"polite\" aria-labelledby=\"calc-reactions-title\"><p id=\"calc-reactions-title\" class=\"text-sm text-gray-500 text-center mb-2\">Bu sonu\u00e7 hakk\u0131nda ne d\u00fc\u015f\u00fcn\u00fcyorsunuz?<\/p><div role=\"group\" aria-labelledby=\"calc-reactions-title\" class=\"grid grid-cols-3 sm:flex sm:flex-row sm:justify-around gap-4 sm:items-center sm:flex-wrap\"><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"like\"><span class=\"reaction-count\" data-reaction-count=\"like\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude00 <\/span><span class=\"reaction-description font-medium\">Be\u011fendim <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"helpful\"><span class=\"reaction-count\" data-reaction-count=\"helpful\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\udca1 <\/span><span class=\"reaction-description font-medium\">Faydal\u0131 <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"confused\"><span class=\"reaction-count\" data-reaction-count=\"confused\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude15 <\/span><span class=\"reaction-description font-medium\">Kafam kar\u0131\u015ft\u0131 <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"disappointed\"><span class=\"reaction-count\" data-reaction-count=\"disappointed\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\ud83d\ude1e <\/span><span class=\"reaction-description font-medium\">Hayal k\u0131r\u0131kl\u0131\u011f\u0131 <\/span><\/button><button type=\"button\" aria-pressed=\"false\" class=\"reaction-btn flex flex-col items-center gap-1 text-sm text-gray-700 hover:text-primary-600 cursor-pointer transition-transform hover:scale-105\" data-reaction=\"inaccurate\"><span class=\"reaction-count\" data-reaction-count=\"inaccurate\">0<\/span><span class=\"reaction text-3xl\" aria-hidden=\"true\">\u274c <\/span><span class=\"reaction-description font-medium\">Hatal\u0131 <\/span><\/button><\/div><div id=\"reaction-message\" class=\"hidden mt-8 rounded-md border border-primary-100 bg-white\/50 backdrop-blur-sm px-4 py-2 text-sm text-center shadow-sm\"><\/div><\/section><div class=\"calcdash-ad not-prose calcdash-ad--calc_result calcdash-ad--in-article\"><ins class=\"adsbygoogle\" style=\"display:block\" data-ad-client=\"ca-pub-1721569815777345\" data-ad-slot=\"6317458308\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\"><\/ins><script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script><\/div>\n<style id=\"wpcoderpro-inline-1\">.formula-box {\r\n\tborder-bottom: none !important;\r\n}<\/style><section class=\"formula-box\" aria-labelledby=\"formula-title\">\r\n\t<div id=\"formula-title\" class=\"not-prose font-display mb-4\"><span class=\"icon icon-formula\" aria-hidden=\"true\"><\/span><h2>Serum ozmolalite form\u00fcl\u00fc<\/h2><\/div>\r\n\t<figure class=\"not-prose formula\">\r\n\t\t<figcaption class=\"formula-title\">Form\u00fcl<\/figcaption>\r\n\t\t<div class=\"text-base text-gray-800\" id=\"formula\">\n\\[ \\text{Ozm} = 2 \\times \\text{Na} + \\frac{\\text{Glukoz}}{18} + \\frac{\\text{BUN}}{2.8} + \\frac{\\text{Etanol}}{3.7} \\]\n<\/div>\r\n\t<\/figure>\r\n\t<\/p>\n<p><strong>Burada:<\/strong><\/p>\n<ul>\n<li>\\(\\text{Ozm}\\) \u2014 hesaplanan serum ozmolalitesi (mOsm\/kg)<\/li>\n<li>\\(\\text{Na}\\) \u2014 serum sodyumu (mEq\/L; say\u0131sal olarak mmol\/L ile ayn\u0131d\u0131r)<\/li>\n<li>\\(\\text{Glukoz}\\) \u2014 serum glukozu, mg\/dL cinsinden<\/li>\n<li>\\(\\text{BUN}\\) \u2014 kan \u00fcre azotu, mg\/dL cinsinden<\/li>\n<li>\\(\\text{Etanol}\\) \u2014 serum etanol\u00fc, mg\/dL cinsinden (iste\u011fe ba\u011fl\u0131 terim; \u00f6l\u00e7\u00fclmediyse eklenmez)<\/li>\n<\/ul>\n<p>Bu form\u00fcl, kan plazmas\u0131ndaki ozmotik olarak etkin par\u00e7ac\u0131klar\u0131n deri\u015fiminin yatak ba\u015f\u0131 bir tahminidir. Mg\/dL cinsinden her bir \u00e7\u00f6z\u00fcnen, molek\u00fcl a\u011f\u0131rl\u0131\u011f\u0131 \u00e7arpan\u0131na b\u00f6l\u00fcnerek mmol\/L'ye \u00e7evrilir; sodyum ise e\u015fit say\u0131da anyonla e\u015fle\u015fti\u011fi i\u00e7in ikiyle \u00e7arp\u0131l\u0131r.<\/p>\n<p>\u00d6l\u00e7\u00fclm\u00fc\u015f bir ozmolalite de\u011feri varsa <strong>ozmolar a\u00e7\u0131kl\u0131k<\/strong> \u015f\u00f6yle hesaplan\u0131r:<\/p>\n<p>\\[ \\text{Ozmolar a\u00e7\u0131kl\u0131k} = \\text{Ozm}_{\\text{\u00f6l\u00e7\u00fclen}} - \\text{Ozm}_{\\text{hesaplanan}} \\]<br \/>\r\n<\/section>\n<style id=\"wpcoderpro-inline-2\">.calculation-box {\r\n\tborder-bottom: none !important;\r\n}<\/style><section id=\"calculation\" class=\"calculation-box\" aria-labelledby=\"calculation-title\">\r\n\t<div id=\"calculation-title\" class=\"not-prose font-display\"><span class=\"icon icon-unordered-list\" aria-hidden=\"true\"><\/span><h2>Serum ozmolalitesi \u2013 hesaplama \u00f6rne\u011fi<\/h2><\/div>\r\n\r\n<\/p>\n<p><strong>\u00d6rnek:<\/strong> serum sodyumu 140 mEq\/L, glukozu 100 mg\/dL, BUN'u 15 mg\/dL olan ve \u00f6l\u00e7\u00fclebilir d\u00fczeyde etanol\u00fc bulunmayan bir hasta.<\/p>\n<p>\\[ \\text{Ozm} = 2 \\times 140 + \\frac{100}{18} + \\frac{15}{2.8} \\]<\/p>\n<p>\\[ \\text{Ozm} = 280 + 5,6 + 5,4 = 290,9 \\text{ mOsm\/kg} \\]<\/p>\n<p><strong>Sonu\u00e7:<\/strong> hesaplanan serum ozmolalitesi yakla\u015f\u0131k 291 mOsm\/kg'd\u0131r ve bu, 275\u2013295 mOsm\/kg'l\u0131k normal referans aral\u0131\u011f\u0131 i\u00e7indedir. Laboratuvar ayr\u0131ca, \u00f6rne\u011fin, 295 mOsm\/kg'l\u0131k bir \u00f6l\u00e7\u00fclm\u00fc\u015f ozmolalite bildirmi\u015f olsayd\u0131, ozmolar a\u00e7\u0131kl\u0131k \\( 295 - 290,9 = 4,1 \\) mOsm\/kg olurdu \u2014 o da normaldir.<\/p>\n<p>\n\r\n<\/section>\n<h2>Hesaplay\u0131c\u0131 nas\u0131l kullan\u0131l\u0131r?<\/h2>\n<ol>\n<li><strong>Serum sodyum<\/strong> de\u011ferinizi mEq\/L cinsinden girin (raporunuz mmol\/L kullan\u0131yorsa ayn\u0131 say\u0131y\u0131 yaz\u0131n).<\/li>\n<li><strong>Serum glukoz<\/strong> de\u011ferinizi girin ve alan\u0131n yan\u0131ndaki birim se\u00e7iciden <strong>mg\/dL<\/strong> ya da <strong>mmol\/L<\/strong> se\u00e7in.<\/li>\n<li><strong>Kan \u00fcre azotu (BUN)<\/strong> de\u011ferinizi girin ve birimini se\u00e7in. Raporunuzda \u00fcre mmol\/L olarak verildiyse o de\u011feri girip mmol\/L'yi se\u00e7in; hesaplay\u0131c\u0131 d\u00f6n\u00fc\u015f\u00fcm\u00fc sizin yerinize yapar.<\/li>\n<li>Etanol d\u00fczeyi \u00f6l\u00e7\u00fcld\u00fcyse <strong>Etanol (iste\u011fe ba\u011fl\u0131)<\/strong> alan\u0131na do\u011fru birimle girin; \u00f6l\u00e7\u00fclmediyse 0 olarak b\u0131rak\u0131n.<\/li>\n<li>Laboratuvar ozmolaliteyi do\u011frudan \u00f6l\u00e7m\u00fc\u015fse, ozmolar a\u00e7\u0131kl\u0131\u011f\u0131 hesaplamak i\u00e7in <strong>\u00d6l\u00e7\u00fclen ozmolalite (iste\u011fe ba\u011fl\u0131)<\/strong> alan\u0131na yaz\u0131n. Elinizde yaln\u0131zca hesaplanan de\u011fer varsa bu alan\u0131 bo\u015f b\u0131rak\u0131n.<\/li>\n<li><strong>Hesaplanan serum ozmolalitesini<\/strong>, <strong>ozmolar a\u00e7\u0131kl\u0131\u011f\u0131<\/strong> (\u00f6l\u00e7\u00fclen de\u011fer girildiyse) ve altlar\u0131ndaki yorum metnini okuyun.<\/li>\n<\/ol>\n<h2>Serum ozmolalitesi nedir?<\/h2>\n<p>Serum ozmolalitesi, kandaki \u00e7\u00f6z\u00fcnm\u00fc\u015f ve ozmotik olarak etkin par\u00e7ac\u0131klar\u0131n toplam deri\u015fimini ifade eder; bunlar\u0131n ba\u015f\u0131nda sodyum ve ona e\u015flik eden anyonlar, ayr\u0131ca glukoz ve \u00fcre gelir. De\u011fer, kilogram su ba\u015f\u0131na miliosmol (mOsm\/kg) cinsinden verilir. Ozmolalite, suyun v\u00fccut b\u00f6lmeleri aras\u0131nda hareketini y\u00f6netti\u011finden s\u0131v\u0131 dengesi bozuluklar\u0131n\u0131n de\u011ferlendirilmesinde merkezi bir yer tutar.<\/p>\n<p>Ozmolalite bir ozmometreyle do\u011frudan \u00f6l\u00e7\u00fclebilmekle birlikte, bir\u00e7ok klinik durumda rutin biyokimya de\u011ferlerinden hesaplanan tahmine g\u00fcvenilebilir. Normal aral\u0131k kabaca 275\u2013295 mOsm\/kg'd\u0131r. 275'in alt\u0131ndaki bir de\u011fer, en s\u0131k hiponatremiden kaynaklanan hipo-ozmolaliteye i\u015faret eder; 295'in \u00fcst\u00fc ise, ba\u015fta hiperglisemi, dehidratasyon ya da \u00fcre y\u00fckselmesine yol a\u00e7an b\u00f6brek yetmezli\u011fi olmak \u00fczere, hiperozmolalite anlam\u0131na gelir. 320 mOsm\/kg'n\u0131n \u00fczerindeki belirgin y\u00fckselmeler t\u0131bbi acil durum olu\u015fturur.<\/p>\n<p><strong>Ozmolar a\u00e7\u0131kl\u0131k<\/strong>, \u00f6l\u00e7\u00fclen ozmolalite ile hesaplanan tahmini kar\u015f\u0131la\u015ft\u0131r\u0131r. Yakla\u015f\u0131k \u221210 ile +10 mOsm\/kg aras\u0131ndaki a\u00e7\u0131kl\u0131k normal kabul edilir. Anlaml\u0131 derecede y\u00fcksek bir a\u00e7\u0131kl\u0131k, kanda form\u00fcl\u00fcn hesaba katmad\u0131\u011f\u0131 ozmotik etkin maddeler var demektir; klasik nedenler aras\u0131nda toksik alkol zehirlenmeleri (metanol, etilen glikol), diyabetik ketoasidozdaki aseton, mannitol tedavisi ve radyokontrast maddeler say\u0131labilir. B\u00fcy\u00fck negatif bir a\u00e7\u0131kl\u0131k ise al\u0131\u015f\u0131lmad\u0131kt\u0131r ve genellikle tekrarlanmas\u0131 gereken bir laboratuvar hatas\u0131na i\u015faret eder.<\/p>\n<h2>Varsay\u0131mlar, s\u0131n\u0131rl\u0131l\u0131klar ve pratik ipu\u00e7lar\u0131<\/h2>\n<ul>\n<li><strong>Sonu\u00e7 bir tahmindir, \u00f6l\u00e7\u00fcm de\u011fil.<\/strong> Hesaplanan ozmolalite, form\u00fcl potasyum, kalsiyum ve proteinler gibi k\u00fc\u00e7\u00fck \u00e7\u00f6z\u00fcnenleri yok sayd\u0131\u011f\u0131 i\u00e7in, genellikle do\u011frudan \u00f6l\u00e7\u00fclen de\u011ferden yakla\u015f\u0131k 5\u201310 mOsm\/kg d\u00fc\u015f\u00fck \u00e7\u0131kar.<\/li>\n<li><strong>Etanol varsa hesaba kat\u0131n.<\/strong> Zehirlenmi\u015f hastalarda etanol teriminin atlanmas\u0131, ozmolar a\u00e7\u0131kl\u0131\u011f\u0131 yapay olarak y\u00fckseltip toksik alkol al\u0131m\u0131n\u0131 taklit edebilir. Metanol veya etilen glikol ku\u015fkusu da varsa, etanol hesaba kat\u0131ld\u0131ktan sonra kalan a\u00e7\u0131kl\u0131k klinik olarak anlaml\u0131 sinyaldir.<\/li>\n<li><strong>Birim d\u00f6n\u00fc\u015f\u00fcm\u00fc \u00f6nemlidir.<\/strong> Glukoz i\u00e7in 1 mmol\/L \u2248 18 mg\/dL, \u00fcre i\u00e7in 1 mmol\/L \u2248 2,8 mg\/dL BUN ve etanol i\u00e7in 1 mmol\/L \u2248 4,6 mg\/dL'dir. De\u011ferleri girmeden \u00f6nce laboratuvar raporunuzun hangi birimi kulland\u0131\u011f\u0131n\u0131 mutlaka kontrol edin.<\/li>\n<li><strong>Tek ba\u015f\u0131na hesaplanan de\u011ferin s\u0131n\u0131r\u0131 vard\u0131r.<\/strong> Yorum her zaman klinik tablo, di\u011fer laboratuvar sonu\u00e7lar\u0131 ve varsa \u00f6l\u00e7\u00fclm\u00fc\u015f ozmolalite ile birlikte yap\u0131lmal\u0131d\u0131r. Bu ara\u00e7 yaln\u0131zca bilgi ama\u00e7l\u0131d\u0131r ve t\u0131bbi tan\u0131 yerine ge\u00e7mez.<\/li>\n<\/ul>\n<p>Bu hesaplay\u0131c\u0131y\u0131 tamamlayan ilgili ara\u00e7lar: ileri hiperglisemide sodyumun kendisi seyrelir, bu y\u00fczden bu hesaplay\u0131c\u0131y\u0131 <a href=\"https:\/\/wpcalc.com\/tr\/tisbi\/duzeltilmis-sodyum-hesaplama\/\">D\u00fczeltilmi\u015f Sodyum hesaplay\u0131c\u0131s\u0131yla<\/a> birlikte kullan\u0131n; hipernatremi tedavisinde <a href=\"https:\/\/wpcalc.com\/tr\/tisbi\/serbest-su-acigi\/\">Serbest Su A\u00e7\u0131\u011f\u0131 hesaplay\u0131c\u0131s\u0131<\/a> yerine koyma planlamas\u0131na yard\u0131mc\u0131 olur; y\u00fckselmi\u015f BUN ozmolaliteyi art\u0131rd\u0131\u011f\u0131ndan, altta yatan b\u00f6brek i\u015flevini de\u011ferlendirmek i\u00e7in <a href=\"https:\/\/wpcalc.com\/tr\/tisbi\/egfr-hesaplama-ckd-epi-2021\/\">eGFR hesaplay\u0131c\u0131s\u0131<\/a> yararl\u0131d\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sodyum, glukoz, BUN ve istenirse etanol de\u011ferlerinden serum ozmolalitesini hesaplay\u0131n; \u00f6l\u00e7\u00fclm\u00fc\u015f bir de\u011fer varsa ozmolar a\u00e7\u0131kl\u0131\u011f\u0131 da bulun. mg\/dL veya mmol\/L cinsinden laboratuvar de\u011ferlerinizi girin, an\u0131nda yorumlay\u0131n.<\/p>\n","protected":false},"author":3168,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[11],"tags":[33],"class_list":["post-4061","post","type-post","status-publish","format-standard","hentry","category-tisbi","tag-tani"],"acf":[],"_links":{"self":[{"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/posts\/4061","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/users\/3168"}],"replies":[{"embeddable":true,"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/comments?post=4061"}],"version-history":[{"count":0,"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/posts\/4061\/revisions"}],"wp:attachment":[{"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/media?parent=4061"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/categories?post=4061"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wpcalc.com\/tr\/wp-json\/wp\/v2\/tags?post=4061"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}